| B |
| Best Western Plus Eastgate Inn & SuitesBest Western Plus | 3840 Eastgate Drive, Eastgate | | | |
| C |
| Chateau Regina Hotel & Suites | Glen Elm Park South, no street on record | | | |
| Comfort Inn ReginaComfort Inn | 3221 Eastgate Drive, Eastgate | | | |
| Comfort Suites | 4300 Diefenbaker Drive, Lakeridge | | | |
| Country Inn & Suitesnot edited since 2019 | 3321 Eastgate Drive, Eastgate | countryinns.com | +1-306-789-9117 | |
| Country Inn & Suites by Radisson, Regina, SKCountry Inn & Suites | 3321 Eastgate Bay, Eastgate | radissonhotels.com | +1-306-789-9117 | |
| Courtyard | 1717 Victoria Avenue, Gladmer Park | | | |
| D |
| Days Inn - ReginaDays Inn | 3875 Eastgate Drive, Eastgate | | | |
| Days Inn - Regina Airport WestDays Inn | Lewvan Park, no street on record | | | |
| Delta Hotels ReginaDelta Hotels | 1919 Saskatchewan Drive, Downtown | | | |
| DoubleTree by Hilton Hotel & Conference Centre ReginaDoubleTree | 1975 Broad Street, Heritage | | +1-306-525-6767 | |
| E |
| Econo Lodge | 1735 Prince of Wales Drive, Eastgate | choicehotels.com | | |
| Empire Hotel | Downtown, no street on record | | | |
| F |
| Fairfield Inn & Suites by Marriott Regina | 3915 Albert Street, Lakeview Place | | | |
| Four Points by Sheraton ReginaFour Points by Sheraton | Downtown, no street on record | | | |
| H |
| Hampton Inn & Suites by Hilton Regina East GateHampton | 3830 Eastgate Drive, Eastgate | | | |
| Holiday Inn Express Regina Southnot edited since 2019 | 4255 Albert Street, Qu'Appelle Village | ihg.com | +1-877-660-8550 | |
| Holiday Inn Hotel & Suites ReginaHoliday Inn | 1800 Prince of Wales Drive, Eastgate | | +1-306-789-3883 | |
| Home Inn & Suites by d3h | 3841 Eastgate Drive, Eastgate | | +1-306-522-4434 | |
| Home Inn & Suites Regina Airport | 4801 Harbour Landing Drive, Lewvan Park | homeinnreginaairport.ca | +1-306-546-4663 | |
| Hotel Saskatchewan Radisson Plaza | 2125 Victoria Avenue, Downtown | | | |
| Q |
| Quality Inn & Suites Regina DowntownQuality Inn & Suites | 1907 11th Avenue, Downtown | choicehotels.com | +1 3065694600 | |
| R |
| Ramada Plaza Regina DowntownRamada | 1818 Victoria Avenue, Downtown | | | |
| Residence Inn | Pioneer Village, no street on record | | | |
| S |
| Sandman Hotel & Suites Regina | 1800 Victoria Avenue E, Glen Elm Park | sandmanhotels.ca | | |
| SureStay Plus Hotel by Best Western Seven OaksBest Western | Washington Park, no street on record | surestayplussevenoaks.com | | |
| T |
| The Atlas | 4177 Albert Street, Qu'Appelle Village | | | |
| Trademark Collection | Qu'Appelle Village, no street on record | | | |
| W |
| Wingate by Wyndham Regina | 1700 Broad Street, Downtown | | | |