| A |
| Airbnb Britanot edited since 2017 | 6614 Avenida de Las Pescas, The Muirlands | | | |
| B |
| Bahia Resort Hotel | 998 West Mission Bay Drive, South Mission Beach | bahiahotel.com | +1 858 488 0551 | |
| Bay Inn & Suites | 3325 Midway Drive, Midway District | | | |
| Best Western Americana InnBest Western | 815 West San Ysidro Boulevard, Sunset | bestwestern.com | +1 619-428-5521 | |
| Best Western Inn & Suites San Diego - Zoo/SeaWorld AreaBest Western | 2485 Hotel Circle Place, Silver Terrace | | | |
| Best Western Plus Bayside InnBest Western Plus | 555 West Ash Street, Little Italy | bestwestern.com | +1 619-233-7500 | |
| Best Western San Diego/Miramar HotelBest Western | 9310 Kearny Mesa Road, Miramar Gateway | bestwestern.com | +1 858-578-6600 | |
| Best Western Seven SeasBest Western | 411 Hotel Circle South, Fashion Valley | bestwestern.com | +1 619-291-1300 | |
| C |
| Catamaran Resort Hotel and Spa | 3999 Mission Boulevard, Sail Bay | catamaranresort.com | +18584881081 | |
| Cormorant Botique Hotel | 1110 Prospect Street, Village of La Jolla | cormorantlajolla.com | | |
| Country Inn & Suites | 5975 Lusk Boulevard, Sorrento Mesa | radissonhotels.com | +1 858-558-1818 | |
| Courtyard | 9650 Scranton Road, Barnes Canyon | marriott.com | +1 858-558-9600 | |
| Courtyard San Diego Airport/Liberty StationCourtyard | 2592 Laning Road, Liberty Station | marriott.com | +1 619-221-1900 | |
| Courtyard San Diego CentralCourtyard | 8651 Spectrum Center Boulevard, Kearny Mesa | marriott.com | +1 858-573-0700 | |
| Courtyard San Diego Rancho BernardoCourtyard | 11611 Bernardo Plaza Court, Rancho Bernardo | marriott.com | +1 858-613-2000 | |
| D |
| Days Inn by Wyndham Mission Valley Qualcomm Stadium/ SDSUDays Inn | 5343 Adobe Falls Road, Allied Gardens | wyndhamhotels.com | +1 619-436-4637 | |
| Days Inn by Wyndham San Diego/Downtown/Convention CenterDays Inn | 833 Ash Street, Cortez Hill | wyndhamhotels.com | +1 619-272-6175 | |
| DoubleTree by Hilton Hotel San Diego - Mission ValleyDoubleTree | 7452 Hazard Center Drive, Mission Center | hilton.com | | |
| E |
| Embassy Suites | 4550 La Jolla Village Drive, University Towne Center | hilton.com | +1 858-453-0400 | |
| Estancia La Jolla Hotel & Spa | 9700 North Torrey Pines Road, La Jolla Farms | | | |
| F |
| Fairfield Inn & Suites San Diego Old TownFairfield Inn & Suites | Mission Hills, no street on record | | | |
| Fairmont Grand Del MarFairmont | 5300 Grand del Mar Court, Carmel Country Highlands | fairmont.com | | |
| G |
| Gaslamp Quarter Hotel | 417 Market Street, Gaslamp Quarter | gaslampquarterhotel.com | +1-877-350-0053 | |
| H |
| Hilton Garden Inn | 3805 Murphy Canyon Road, StoneCrest | hilton.com | +1 858-278-9300 | |
| Hilton Garden Inn San Diego Del MarHilton Garden Inn | 3939 Ocean Bluff Avenue, Torrey Hills | hilton.com | | |
| Holiday Inn Express & SuitesHoliday Inn Express | 6705 la Jolla Boulevard, Beach Barber Tract | ihg.com | +1 858-454-7101 | |
| Holiday Inn Express Mira MesaHoliday Inn Express | 9888 Mira Mesa Boulevard, Mira Mesa Gateway | ihg.com | +1-888-465-4329 | |
| Holiday Inn Express San Diego-Sea World AreaHoliday Inn Express | 3950 Jupiter Street, Loma Portal | hiexpress.com | +1 619-226-8000 | |
| Hotel Republic San Diego, Autograph CollectionAutograph Collection | 421 West B Street, Core–Columbia | marriott.com | +1-619-398-3100 | |
| Humphreys Half Moon InnBartell Hotels | 2303 Shelter Island Drive, Roseville | halfmooninn.com | +1-619-224-3411 | |
| Hyatt Regency La Jolla at AventineHyatt Regency | 3777 La Jolla Village Drive, La Jolla Village | hyatt.com | +1 858-552-1234 | |
| I |
| Island Palms Hotel & Marina | 2051 Shelter Island Drive, La Playa | islandpalms.com | +1-619-222-0561 | |
| L |
| La Jolla Shores Hotel | 8110 Camino del Oro, La Jolla Shores | ljshoreshotel.com | +1-858-459-8271 | |
| Lamplighter Inn & Suites at SDSUnot edited since 2022 | 6474 El Cajon Blvd, Rolando | lamplighter-inn.com | +1-619-582-3088 | |
| Legacy Resort Hotel & Spa | 875 Hotel Circle South, Hotel Circle | legacyresortandspa.com | +1-888-534-2299 | |
| M |
| Manchester Grand Hyatt San DiegoHyatt | 1 Market Place, Marina | manchestergrand.hyatt.com | +1 619-232-1234 | |
| Motel San Diego | 4780 Mission Bay Dr, Eureka Lemon | | +1 858-273-6533 | |
| O |
| Old Town Inn | 4444 Pacific Highway, Old Town | oldtown-inn.com | +1-619-260-8024 | |
| P |
| Pacific Shores Innnot edited since 2020 | 4802 Mission Boulevard, North Pacific Beach | pacificshoresinn.com | +1-858-483-6300 | |
| Pleasant Inn | 5550 Clairemont Mesa Boulevard, East Clairemont | | +1 858-560-4551 | |
| Q |
| Quality Inn San Diego I-5 Naval Base | 3878 Dalbergia Court, Shelltown | | +1-619-238-2788 | |
| R |
| Ramada Suites San DiegoRamada | 631 Camino del Rio South, Mission Valley | wyndhamhotels.com | +1 619-762-5689 | |
| Residence Inn San Diego Del MarResidence Inn | 3525 Valley Centre Drive, Carmel View | marriott.com | +1 858-481-8800 | |
| S |
| Sonesta ES Suites | 11855 Avenue of Industry, Carmel Mountain Ranch | | | |
| SpringHill Suites San Diego Mission ValleySpringHill Suites | 2315 Camino del Rio North, Rio Vista | marriott.com | +1 619-582-2838 | |
| Synergy at Mira Bellanot edited since 2021 | 3455 Kearny Villa Road, Serra Mesa | | | |
| T |
| The Dana On Mission BayIndependentnot edited since 2022 | 1710 West Mission Bay Drive, Vacation Isle | thedana.com | +1 619-222-6440 | |
| The Keating Hotel | 432 F Street, Downtown San Diego | thekeating.com | +1-619-814-5700 | |
| The Lafayette Hotel, Swim Club & Bungalows | 2223 El Cajon Boulevard, University Heights | lafayettehotelsd.com | +1-619-296-2101 | |
| V |
| Vantaggio Suites Extended Stays | 819 University Avenue, Hillcrest | vantaggiosuites.com | | |