| A |
| Acturis | 12-22 Newhall Street, Jewellery Quarter | acturis.com | +44 2070794000 | |
| B |
| Blue Apple Productsnot edited since 2014 | Rea Valley, no street on record | | | |
| Brave CX Limited | 12-22 Newhall Street, Jewellery Quarter | bravecx.com | +44 7584256641 | |
| C |
| Cartel Communicationsnot edited since 2010 | Park Central, no street on record | | | |
| Cloud P | 45 Church Street, Jewellery Quarter | cloud-p.com | +44 121 693 9777 | |
| Cornerstone VR | 122 Colmore Row, Jewellery Quarter | cornerstonevr.co.uk | +44 808 1756 414 | |
| CoStar Group | 8 Cherry Street, Digbeth | costar.com | +44 20 3205 4500 | |
| D |
| DocuWare Ltd | 170 Edmund Street, Jewellery Quarter | start.docuware.com | +44 115 718 0353 | |
| E |
| ebs | Tyburn, no street on record | ebs.tech | | |
| EveryHost | 126 Colmore Row, Jewellery Quarter | everyhost.co.uk | +44 333 577 6191 | |
| Express Networks Cybersecurity Services | 23 Colmore Row, Jewellery Quarter | expressnetworks.co.uk | +44 121 816 0511 | |
| F |
| Facepunch Studios LtdFacepunch Studios | 103 Colmore Row, Jewellery Quarter | facepunch.com | | |
| Friend MTS | 45 Church Street, Jewellery Quarter | friendmts.com | +44 121 633 5750 | |
| G |
| Gawooni Games Plc. | 170 Edmund Street, Jewellery Quarter | gawooni.company | +49 69 34700918 | |
| Growth Dental | 1 Victoria Square, Park Central | growthdental.com | +44 121 573 0200 | |
| I |
| Innervation Telecommunicationsnot edited since 2013 | Rea Valley, no street on record | | | |
| K |
| Kagool UK Ltd. | Regency Wharf, Park Central | kagool.com | +44 333 939 9949 | |
| Kainos | 2 Cornwall Street, Jewellery Quarter | kainos.com | +44 289 057 1100 | |
| Kal Enterprises | 23 Colmore Row, Jewellery Quarter | kals.enterprises | +44 7933 585650 | |
| O |
| OneAdvanced | Park Central, no street on record | | | |
| P |
| Port P | 45 Church Street, Jewellery Quarter | port-p.com | +44 121 693 9666 | |
| Pro Expert Web Design | 103 Colmore Row, Jewellery Quarter | proexpertwebdesignbirmingham.co.uk | +44 1217240352 | |
| Q |
| Qure.ai Technologies | 170 Edmund Street, Jewellery Quarter | qure.ai | | |
| S |
| ServiceteamIT | Edgbaston, no street on record | | | |
| Silktide | 16 Barwick Street, Jewellery Quarter | silktide.com | +44 1332 460460 | |
| Softcat | 134 Edmund Street, Jewellery Quarter | softcat.com | +44 121 752 6900 | |
| Spenny Piggy | 55 Colmore Row, Jewellery Quarter | spennypiggy.co | +44 20 3355 2057 | |
| Squibble | 55 Colmore Row, Jewellery Quarter | squibble.design | +44 121 448 4776 | |
| System Automate | 55 Colmore Row, Jewellery Quarter | systemautomate.com | +44 7401 446 184 | |
| T |
| TalkTalknot edited since 2014 | Ladywood, no street on record | | | |
| The Process Play | 55 Colmore Row, Jewellery Quarter | theprocessplay.com | +44 7939837829 | |
| The SaaSy People | 47 Cannon Street, Digbeth | thesaasypeople.com | +44 121 312 9919 | |
| V |
| Vantinot edited since 2021 | 44 Upper Gough Street, Park Central | | | |
| W |
| WinMan ERP Softwarenot edited since 2013 | Hodge Hill, no street on record | | | |
| Z |
| ZapTick AI | 1 Victoria Square, Park Central | zaptick.ai | +44 7440756897 | |