| A |
| Almaden Technology Groupnot edited since 2021 | 6455 Almaden Expressway, Almaden Valley | | | |
| AnDapt | 950 South Bascom Avenue, Buena Vista | | | |
| ASAP Systemsnot edited since 2021 | 355 Piercy Road, Silver Creek | asapsystems.com | | |
| ASMLnot edited since 2022 | 80 West Tasman Drive, Alviso | | | |
| Audavinot edited since 2021 | 1310 Tully Road, Seven Trees | audavi.com | | |
| Avocado Systemsnot edited since 2021 | 2150 Trade Zone Boulevard, Berryessa | avocadosys.com | | |
| aXcelerate Networks | 490 North 1st Street, Japantown | axceleratenetworks.com | | |
| B |
| BCL Technologies | 950 South Bascom Avenue, Buena Vista | | | |
| Beachhead Solutions | 1150 South Bascom Avenue, Buena Vista | beachheadsolutions.com | | |
| BellSoft | 111 North Market Street, Japantown | bell-sw.com | +1-702-213-5959 | |
| C |
| Calix Incorporated | 2777 Orchard Parkway, Alviso | | | |
| Cisco | 3098 Olsen Drive, Rose Garden | splunk.com | +1-866-438-7758 | |
| Cisco Systems Building 13 | 3675 Cisco Way, Alviso | | | |
| Cisco Systems Building P | 125 West Tasman Drive, Alviso | | | |
| Coppercone | 1475 Saratoga Avenue, Buena Vista | coppercone.com | | |
| CY Visionnot edited since 2021 | 101 Metro Drive, Japantown | cyvision.com | | |
| D |
| Devicenet USA Inc. | 4000 Moorpark Avenue, Rose Garden | | | |
| Diamantinot edited since 2021 | 111 North Market Street, Japantown | diamanti.com | | |
| E |
| Epam | 2055 Gateway Place, Japantown | epam.com | +1 267 759 9000 | |
| G |
| GEM Optoelectronicnot edited since 2022 | 1141 Ringwood Court, Berryessa | gem-oe.com | | |
| GEO Semiconductornot edited since 2021 | 101 Metro Drive, Japantown | geosemi.com | | |
| I |
| iPlum | 950 South Bascom Avenue, Buena Vista | | | |
| L |
| Longcheer Technology (U.S.) Limited | 1620 Oakland Road, Berryessa | longcheer.com | | |
| Lyftnot edited since 2022 | 743 South Winchester Boulevard, Buena Vista | | | |
| M |
| MediaAgility | 1475 Saratoga Avenue, Buena Vista | | | |
| Meridian Computer Systems | 1777 Hamilton Avenue, Dry Creek | | +1-408-979-9944 | |
| Monolithic Power Systemsnot edited since 2021 | 79 Great Oaks Boulevard, Silver Creek | | | |
| Myers Network Solutions | 1101 South Winchester Boulevard, Buena Vista | myersnetsol.com | +1 408 483-1881 | |
| N |
| NetApp | 3060 Olsen Drive, Rose Garden | netapp.com | +1 408-822-6000 | |
| Nevtec | 1150 South Bascom Avenue, Buena Vista | nevtec.com | | |
| Nutanix | 1740 Technology Drive, Japantown | nutanix.com | | |
| O |
| Oactel | 275 East Taylor Street, Japantown | oactel.com | | |
| P |
| Pandoranot edited since 2021 | 2150 Trade Zone Boulevard, Berryessa | | | |
| PayActiv, Incnot edited since 2021 | 4880 Stevens Creek Boulevard, Rose Garden | | | |
| PropertyMinder | 1101 South Winchester Boulevard, Buena Vista | propertyminder.com | | |
| R |
| Roku 1 | 1143 Coleman Avenue, Rose Garden | | | |
| Roku 2 | 1155 Coleman Avenue, Rose Garden | | | |
| Roku 3 | 1173 Coleman Avenue, Rose Garden | | | |
| Roku 4 | 1167 Coleman Avenue, Rose Garden | | | |
| Roku, Inc.not edited since 2021 | 1701 Junction Court, Luna Park | | | |
| S |
| Silicon Valley IT Consultingnot edited since 2021 | 4994 Cherry Avenue, Almaden Valley | | | |
| Skycart | 97 East Brokaw Road, Japantown | skycart.net | | |
| Spanner Product Development | 15 West San Fernando Street, Japantown | spannerpd.com | | |
| Stellar IT Solutions | 1620 Oakland Road, Berryessa | stellaritgroup.com | | |
| Supermicro Computers Incnot edited since 2021 | 980 Rock Avenue, Berryessa | | | |
| V |
| VTA Information Technologynot edited since 2020 | Alviso, no street on record | | | |
| W |
| Walkwater Technologies Incorporatednot edited since 2021 | 3150 Almaden Expressway, Dry Creek | | | |
| World IP Phone Inc. | 5149 Moorpark Avenue, Rose Garden | worldipphone.com | | |
| Z |
| Zone24x7not edited since 2021 | 3150 Almaden Expressway, Dry Creek | zone24x7.com | | |
| zSpace, Incnot edited since 2021 | 2728 Orchard Parkway, Alviso | | | |