| B |
| Britannia Airport Hotel | Palatine Road, Northenden | | | | |
| Britannia Country House Hotel | Palatine Road, Didsbury | | | | |
| C |
| City Gate Suitesnot edited since 2022 | St. Chads Street, Strangeways | | | | |
| Clayton HotelClayton Hotels | Outwood Lane, Woodhouse Park | | claytonhotelmanchesterairport.com | | |
| Crowne Plaza | 70 Shudehill, Ancoats | | ihg.com | +44 161 8288600 | |
| D |
| Diamond Lodge | Hyde Road, Belle Vue | | diamondlodge.co.uk | | |
| Dickenson Hotelnot edited since 2008 | Longsight, no street on record | | | | |
| Didsbury House | 11 Didsbury Park, Parrs Wood | | didsburyhouse.co.uk | | |
| DoubleTree | Outwood Road, Woodhouse Park | 4 | hilton.com | +44 161 435 3000 | |
| E |
| Etrop Grange Hotel | Bailey Lane, Woodhouse Park | | english-inns.co.uk | | |
| H |
| Holiday Inn | 888 Oldham Road, Newton Heath | | | | |
| Holiday Inn Express Manchester AirportHoliday Inn Express | Runger Lane, Ringway | | hiexmanchesterairport.co.uk | +44 161 980 2556 | |
| Holiday Inn Express Manchester EastHoliday Inn Express | Wall Way, Gorton | | ihg.com | | |
| Holiday Inn Manchester AirportHoliday Inn | 1 Palma Avenue, Woodhouse Park | | ihg.com | +44 161 2433333 | |
| Hyatt House ManchesterHyatt House | 55 Booth Street West, Hulme | 4 | hyatt.com | +44 1613595556 | |
| Hyatt Regency ManchesterHyatt Regency | 55 Booth Street West, Hulme | 4 | hyatt.com | +44 1613595550 | |
| I |
| Ibis Budget Manchester AirportIbis Budget | 3 Palma Avenue, Woodhouse Park | | all.accor.com | +44 161 388 5211 | |
| Ibis Budget Manchester CentreIbis Budget | 2 Pollard Street, Ancoats | | accor.com | +44 161 272 2020 | |
| ibis Manchester Centre Princess StreetIbis | Charles Street, Brunswick | | | | |
| Innside ManchesterMeliá | First Street, Hulme | | melia.com | +44 161 200 2500 | |
| L |
| Leonardo Hotel Manchester Central | 56 Great Bridgewater Street, City Centre | | leonardohotels.co.uk | +44 161 953 8888 | |
| Leven Hotel | 40 Chorlton Street, City Centre | | liveleven.com | +44 161 359 7900 | |
| Lewis Apartments | 28 Swan Street, Ancoats | | lewisapartmentsmanchester.co.uk | | |
| M |
| Manchester Marriott Hotel PiccadillyMarriott Bonvoy | 91 London Road, Brunswick | | marriott.com | +44 161 272 3200 | |
| Manchester South Hotel | 340 Wilmslow Road, Fallowfield | | | | |
| N |
| Native Manchester by NumaNuma Stays | Ducie Street, Ancoats | | numastays.com | +44 207 221 2028 | |
| New Union Hotel | 111 Princess Street, City Centre | | newunionhotel.co.uk | +44 161 870 0031 | |
| O |
| Oyo Hala Guest Housenot edited since 2019 | 141-143 Dickenson Road, Rusholme | | | | |
| P |
| Park Crescent Hotel | 13 Park Crescent, Rusholme | | | | |
| Park Inn by Radisson Manchester City CentrePark Inn | 4 Cheetham Hill Road, Strangeways | | | | |
| Parkview Residencenot edited since 2021 | 220 Waterloo Road, Cheetham Hill | 3 | parkview-residence.com | +44 161 400 3569 | |
| Pendulum Hotel | Sackville Street, Brunswick | | pendulumhotel.co.uk | | |
| Premier Inn | Crumpsall, no street on record | | premierinn.com | | |
| Premier Inn Heald GreenPremier Inn | Finney Lane, Peel Hall | | premierinn.com | +44 871 527 8734 | |
| Premier Inn Manchester Airport (Runger Lane South)Premier Inn | Runger Lane, Ringway | | listed | | |
| Premier Inn Manchester Airport FT (Runger Lane North)Premier Inn | Runger Lane, Ringway | | listed | | |
| Premier Inn Manchester City Centre (Northern Quarter)Premier Inn | 9 Rochdale Road, Ancoats | | listed | +44 3330 149487 | |
| Premier Inn Manchester West DidsburyPremier Inn | Derwent Avenue, West Didsbury | | premierinn.com | +44 871 527 8722 | |
| R |
| Residence Inn Manchester PiccadillyResidence Inn | 40 Laystall Street, Ancoats | | marriott.com | +44 161 841 7800 | |
| T |
| The Castlefield Hotel | Liverpool Road, City Centre | | castlefield-hotel.co.uk | +44 161 832 7073 | |
| The Fallowfield Lodge | Fallowfield, no street on record | | | | |
| The Mitre | 1-3 Cathedral Gates, City Centre | | mitrehotel.co.uk | +44 161 834 4128 | |
| the niu Loomthe niu | 2 Irish Town Way, Cheetham Hill | | the.niu.de | +44 161 518 0888 | |
| The Parklands Residential Hotelnot edited since 2015 | Collyhurst, no street on record | | | | |
| The Rem Hotel | 33 Sackville Street, City Centre | | therembrandtmanchester.com | +44 161 211 3931 | |
| Travelodge | 227 Upper Brook Street, Chorlton-on-Medlock | | travelodge.co.uk | | |
| Travelodge - Manchester CentralTravelodge | Great Ducie Street, Strangeways | | travelodge.co.uk | | |
| TRIBE | 6 Chicago Avenue, Woodhouse Park | | tribe-manchesterairport.co.uk | +441612437777 | |
| V |
| Victoria Park Hotel | Rusholme, no street on record | | | | |
| W |
| Waterside Hotel | Wilmslow Road, Parrs Wood | | waterside-hotel.co.uk | | |