| A |
| Anstey Residential | 13 Bellevue Road, Bellevue | | | |
| Aspire | Shirley, no street on record | | | |
| Austin & Wyatt | 26 London Road, Bedford Place | austinwyatt.co.uk | +44 2381247027 | |
| Austin & Wyatt | 335 Shirley Road, Shirley | austinwyatt.co.uk | +44 23 8124 7035 | |
| Austin & Wyatt | 369 Bitterne Road, Bitterne | austinwyatt.co.uk | +44 2381247034 | |
| B |
| Beals | Bitterne, no street on record | | | |
| Beals | Shirley Road, Shirley | | | |
| Belvoir | 36 London Road, Bedford Place | | | |
| C |
| Cavendish Homes | 31 Lodge Road, Bevois Mount | | | |
| Century 21 | Bellevue, no street on record | | | |
| Charters Southampton | 73 The Avenue, Bevois Town | chartersestateagents.co.uk | +44 2382 544544 | |
| City and Solent Lettings | 1-4 Cumberland Place, The Polygon | cityandsolent.com | +44 23 8036 1563 | |
| Cryers Residential Lettingsnot edited since 2018 | 38 Bedford Place, Bedford Place | propertywide.co.uk | +44 23 8124 7026 | |
| E |
| Edison Green | Old Town, no street on record | edisongreen.co.uk | | |
| enfields | Bitterne, no street on record | | | |
| Enfields | Shirley, no street on record | | | |
| F |
| Field Palmer | Kingsland Place, no street on record | | | |
| Field Palmer | 24 Portsmouth Road, Woolston | fieldpalmer.com | | |
| Fox & Sons | Bitterne, no street on record | | | |
| Fox & Sons | 32-34 London Road, Bedford Place | | | |
| H |
| Homelife Lettings | 70 Portswood Road, Portswood Park | | +44 23 8058 6838 | |
| Hunters | Bedford Place, no street on record | | | |
| K |
| Kings Estates | 253 Portswood Road, Portswood | kingsestates.net | +44 23 80553355 | |
| KSDnot edited since 2022 | 1A Shirley Road, Shirley | | | |
| L |
| Leaders | Bitterne, no street on record | | | |
| Leaders | Ocean Village, no street on record | | | |
| Leaders | 13 London Road, Bedford Place | leaders.co.uk | | |
| Let's Rent | 20 Portsmouth Road, Woolston | letsrentsouthampton.co.uk | | |
| Links Property | 38 London Road, Bedford Place | | | |
| M |
| Martin & Co | London Road, Bedford Place | | | |
| Morris Dibben | 377-379 Bitterne Road, Bitterne | morrisdibben.co.uk | +44 2381247030 | |
| Morris Dibben | 53 London Road, Bedford Place | morrisdibben.co.uk | +44 2381247004 | |
| Morris Dibben | 38 Portsmouth Road, Woolston | morrisdibben.co.uk | +44 2381247029 | |
| P |
| Pearsonsnot edited since 2022 | Kingsland Place, no street on record | | | |
| Pearsonsnot edited since 2014 | 58-60 London Road, Bedford Place | | | |
| Poswall Lettings | 255 Portswood Road, Portswood | | | |
| S |
| Smart Homesnot edited since 2021 | Bedford Place, no street on record | | | |
| Stanford | Bitterne, no street on record | | | |
| T |
| Tenant Link | 19 London Road, Bedford Place | | | |
| The Home Agency | 11 London Road, Bedford Place | | | |
| The Letting Agencynot edited since 2019 | Bedford Place, no street on record | | | |
| W |
| White & Guard | Bitterne, no street on record | | | |
| Y |
| Your Move | 28 London Road, Bedford Place | your-move.co.uk | | |